MD Biosciences/Myelin Proteolipid Protein (PLP 139-151)/15 mg/301008,MD Biosciences,,MD Biosciences,mdbiosciences,+,,Array.Array蚂蚁淘厂家直采.

产品名称：MD Biosciences/Myelin Proteolipid Protein (PLP 139-151)/15 mg/301008

产品编号：301008

市场价：¥0.00

场地：美国(厂家直采)

产品分类：生化试剂>标准品>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：待定

品牌： MD Biosciences

公司：MDBiosciences

公司分类：

商品介绍

Overview
Literature/Support

Overview

Overview:

Multiple Sclerosis (MS) is a demyelinating disease of the central nervous system (CNS). The main characteristics of the disease are focal areas of demyelination and inflammation, however the pathogenesis is unclear.

Although no animal model thus far establishes all facets of human MS, Experimental Autoimmune Encephalomyelitis (EAE) represents the model most studied for the disease. Initially brain homogenates were used as antigens for immunization. Today, myelin related proteins or peptides are used in the disease.

Literature/Support

Literature/Support/Publications:

Myelin Proteolipid Protein Insert (PDF)

References/Citations:	How Proteolipid protein (PLP) was used:
The novel small molecule drug Rabeximod is effective in reducing disease severity of mouse models of autoimmune disorders M Hultqvist, K S Nandakumar, U Björklund, and R Holmdahl Ann Rheum Dis, Jan 2009; 68: 130 - 135.	Proteolipid protein (PLP) was used to induce EAE in SJL mice by subcutaneous injection.On day 0, 125 ug PLP/300 ug CFA per animal was used for induction and a supplemental immunostimulation with 20 ug/kg pertussis toxin was performed on day 0 and after 48 hrs.

品牌介绍

MD Biosciences成立于1991年，总部位于瑞士，在美国、加拿大和英国设有办事处，是一家领先的研发和临床阶段的制药和生物技术的公司，提供尖端的研究服务，创新的生物产品和先进的诊断能力。我们在炎症和神经学领域拥有超过25年的无与伦比的科学专业知识和专有方法历史，这些使我们一直处于精确医学运动的前沿。

其主要产品包括：

抗体 (软骨蛋白聚糖、胶原蛋白、激素、神经药物)、细胞培养相关试剂 (胶原蛋白、细胞增殖检测、支原体PCR检测)、疾病诱导试剂 (关节炎诱导抗体混合、弗氏佐剂、胶原蛋白II等)、ELISA试剂盒（糖蛋白、细胞因子、激素等）、同型对照、天然蛋白以及重组蛋白（胶原类等）。